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Acknowledgements This work was conducted by Malachi Griffith under the supervision of Marco A. Marra. In addition to the authors and funding sources listed below I would like to acknowledge the advice and support of the following people: Joseph Connors, Stephane Flibotte, Steven Jones and Gregg Morin. Citations: Malachi Griffith and Marco A. Marra. Malachi Griffith, Michelle J. Tang, Obi L. Griffith, Ryan D. Morin, Susanna Y. Chan, Jennifer K. Asano, Thomas Zeng,
Stephane Flibotte, Adrian Ally, Agnes Baross, Martin Hirst, Steven J.M. Jones, Gregg B. Morin, Isabella T. Tai
and Marco A. Marra. Malachi Griffith, Obi L. Griffith, Ryan D. Morin, Michelle J. Tang, Ying-Chen Hou, Trevor J. Pugh, Rodrigo Goya,
Jill Mwenifumbo, Suganthi Chittaranjan, Adrian Ally, Jennifer K. Asano, Susanna Y. Chan, Haiyan I. Li, Helen McDonald,
Kevin Teague, Yongjun Zhao, Thomas Zeng, Allen Delaney, Martin Hirst, Gregg B. Morin, Steven J. M. Jones,
Isabella T. Tai, Marco A. Marra Malachi Griffith, Jessica E. Paul, Trevor J. Pugh, Michelle J. Tang, Ying-Chen Claire Hou, Ryan D. Morin, Jennifer K. Asano, Adrian Ally, Lisa Miao, Pierre Cheung,
Alison Lee, Susanna Y. Chan, Greg Taylor, Tesa Severson, Grace S.W. Cheng, Karen Novik, Richard Moore, Sharlene Gill, David Owen, Carl J. Brown,
Gregg B. Morin, Isabella T. Tai1 and Marco A. Marra. Funding We are grateful for funding provided by the following organizations: the University of British Columbia, Faculty of Graduate Studies and Faculty of Medicine, Michael Smith Foundation for Health Research, Natural Sciences and Engineering Research Council, Genome British Columbia, Terry Fox Foundation, National Cancer Institute of Canada and BC Cancer Foundation.
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